The aloof protagonist: a bookworm who is deeply detached from the world he resides in. He has no interest in others and is firmly convinced that nobody has any interest in him either. His story begins when he stumbles across a handwritten book, titled "Living with Dying." He soon identifies it as a secret diary belonging to his popular, bubbly classmate Sakura Yamauchi. She then confides in him about the pancreatic disease she is suffering from and that her time left is finite. Only her family knows about her terminal illness; not even her best friends are aware. Despite this revelation, he shows zero sympathy for her plight, but caught in the waves of Sakura's persistent buoyancy, he eventually concedes to accompanying her for her remaining days. As the pair of polar opposites interact, their connection strengthens, interweaving through their choices made with each passing day. Her apparent nonchalance and unpredictability disrupts the protagonist's impassive flow of life, gradually opening his heart as he discovers and embraces the true meaning of living. [Written by MAL Rewrite]

Lucy is a special breed of human referred to as "Diclonius," born with a short pair of horns and invisible telekinetic hands that lands her as a victim of inhumane scientific experimentation by the government. However, once circumstances present her an opportunity to escape, Lucy, corrupted by the confinement and torture, unleashes a torrent of bloodshed as she escapes her captors. During her breakout, she receives a crippling head injury that leaves her with a split personality: someone with the mentality of a harmless child possessing limited speech capacity. In this state of instability, she stumbles upon two college students, Kouta and his cousin Yuka, who unknowingly take an injured fugitive into their care, unaware of her murderous tendencies. This act of kindness will change their lives, as they soon find themselves dragged into the shadowy world of government secrecy and conspiracy. [Written by MAL Rewrite]

The rare and inexplicable Puberty Syndrome is thought of as a myth. It is a rare disease which only affects teenagers, and its symptoms are so supernatural that hardly anyone recognizes it as a legitimate occurrence. However, high school student Sakuta Azusagawa knows from personal experience that it is very much real, and happens to be quite prevalent in his school. Mai Sakurajima is a third-year high school student who gained fame in her youth as a child actress, but recently halted her promising career for reasons unknown to the public. With an air of unapproachability, she is well known throughout the school, but none dare interact with her—that is until Sakuta sees her wandering the library in a bunny girl costume. Despite the getup, no one seems to notice her, and after confronting her, he realizes that she is another victim of Puberty Syndrome. As Sakuta tries to help Mai through her predicament, his actions bring him into contact with more girls afflicted with the elusive disease. [Written by MAL Rewrite]

Hachiman Hikigaya is an apathetic high school student with narcissistic and semi-nihilistic tendencies. He firmly believes that joyful youth is nothing but a farce, and everyone who says otherwise is just lying to themselves. In a novel punishment for writing an essay mocking modern social relationships, Hachiman's teacher forces him to join the Volunteer Service Club, a club that aims to extend a helping hand to any student who seeks their support in achieving their goals. With the only other club member being the beautiful ice queen Yukino Yukinoshita, Hachiman finds himself on the front line of other people's problems—a place he never dreamed he would be. As Hachiman and Yukino use their wits to solve many students' problems, will Hachiman's rotten view of society prove to be a hindrance or a tool he can use to his advantage? [Written by MAL Rewrite]