Holo is a powerful wolf deity who is celebrated and revered in the small town of Pasloe for blessing the annual harvest. Yet as years go by and the villagers become more self-sufficient, Holo, who stylizes herself as the "Wise Wolf of Yoitsu," has been reduced to a mere folk tale. When a traveling merchant named Kraft Lawrence stops at Pasloe, Holo offers to become his business partner if he eventually takes her to her northern home of Yoitsu. The savvy trader recognizes Holo's unusual ability to evaluate a person's character and accepts her proposition. Now in the possession of both sharp business skills and a charismatic negotiator, Lawrence inches closer to his goal of opening his own shop. However, as Lawrence travels the countryside with Holo in search of economic opportunities, he begins to realize that his aspirations are slowly morphing into something unexpected. Based on the popular light novel of the same name, Ookami to Koushinryou, also known as Spice and Wolf, fuses the two polar genres of economics and romance to create an enthralling story abundant with elaborate schemes, sharp humor, and witty dialogue. Ookami to Koushinryou is more than just a story of bartering; it turns into a journey of searching for a lost identity in an ever-changing world. [Written by MAL Rewrite]

The aloof protagonist: a bookworm who is deeply detached from the world he resides in. He has no interest in others and is firmly convinced that nobody has any interest in him either. His story begins when he stumbles across a handwritten book, titled "Living with Dying." He soon identifies it as a secret diary belonging to his popular, bubbly classmate Sakura Yamauchi. She then confides in him about the pancreatic disease she is suffering from and that her time left is finite. Only her family knows about her terminal illness; not even her best friends are aware. Despite this revelation, he shows zero sympathy for her plight, but caught in the waves of Sakura's persistent buoyancy, he eventually concedes to accompanying her for her remaining days. As the pair of polar opposites interact, their connection strengthens, interweaving through their choices made with each passing day. Her apparent nonchalance and unpredictability disrupts the protagonist's impassive flow of life, gradually opening his heart as he discovers and embraces the true meaning of living. [Written by MAL Rewrite]

The rare and inexplicable Puberty Syndrome is thought of as a myth. It is a rare disease which only affects teenagers, and its symptoms are so supernatural that hardly anyone recognizes it as a legitimate occurrence. However, high school student Sakuta Azusagawa knows from personal experience that it is very much real, and happens to be quite prevalent in his school. Mai Sakurajima is a third-year high school student who gained fame in her youth as a child actress, but recently halted her promising career for reasons unknown to the public. With an air of unapproachability, she is well known throughout the school, but none dare interact with her—that is until Sakuta sees her wandering the library in a bunny girl costume. Despite the getup, no one seems to notice her, and after confronting her, he realizes that she is another victim of Puberty Syndrome. As Sakuta tries to help Mai through her predicament, his actions bring him into contact with more girls afflicted with the elusive disease. [Written by MAL Rewrite]

On the surface, the thought of Kyouko Hori and Izumi Miyamura getting along would be the last thing in people's minds. After all, Hori has a perfect combination of beauty and brains, while Miyamura appears meek and distant to his fellow classmates. However, a fateful meeting between the two lays both of their hidden selves bare. Even though she is popular at school, Hori has little time to socialize with her friends due to housework. On the other hand, Miyamura lives under the noses of his peers, his body bearing secret tattoos and piercings that make him look like a gentle delinquent. Having opposite personalities yet sharing odd similarities, the two quickly become friends and often spend time together in Hori's home. As they both emerge from their shells, they share with each other a side of themselves concealed from the outside world. [Written by MAL Rewrite]