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The fate of mankind is doomed in the early 21st century due to losing "purana," an essence of living force supporting all life forms. Not willing to witness the extinction of mankind, a vampire named Duo disclosed the secret of purana to humans, saving the latter from destruction. However, just like Prometheus in Greek mythology got punished for bringing fire to mankind, Duo is punished for breaking the taboo. The vampire sent to punish him is Zieg, Duo's best friend, or, more than the best friend. (Source: ANN)

Mitsugu Banba is a high school girl who finds meaning in donating blood. She frequently visits a blood bank to donate blood, despite being harshly treated by the nurse. One day, she encounters a beautiful girl who looks like she's from overseas at the blood bank. The pale girl looks like she's about to faint any minute, but then, she starts destroying the blood bank. The girl loses consciousness and Mitsugu takes her home... (Source: Official Website)

Fifth season of Strike the Blood.